Pantoprazole 20mg tablets belong to a group of medicines called proton pump inhibitors which work by reducing the amount of acid that is produced by your stomach. Pantoprazole 20mg are oval coated tablets which are yellow in colour and come in blister packs or bottles. These tablets are available on prescription only. They must be stored under 30 degs C, and protected from moisture. The capsules should be used before the expiry date. As with all medicines, keep Pantoprazole out of sight and reach of children.
The doctor’s instructions should always be followed exactly when taking Pantoprazole 20mg tablets. The usual dose is one tablet per day but your doctor will tell you how many tablets to take, how long to take them for and this will depend on your condition. You can take your tablet one hour before food and it should be swallowed whole with water and not chewed or crushed. Pantoprazole 20mg can be used for long term management and preventing reflux oesophagitis returning.
Each tablet contains 20mg pantoprazole (as pantoprazole sodium sesquihydrate) which is the active ingredient. They also contain calcium stearate, cellulose microcrystalline, crospovidone, hydroxypropylcellulose (type EXF), sodium carbonate, anhydrous, silica, colloidal anhydrous, hypromellose, iron oxide yellow (E172), macrogol 400, methacrylic acid – ethyl acrylate copolymer (1:1) polysorbate 80, ponceau 4R aluminium lake (E124), quinolone yellow aluminium lake (E104), sodium lauryl sulphate, titanium dioxide (E171), triethyl citrate, macrogol 600, shellac, povidone, iron oxide black (E172), iron oxide red (E172), iron oxide yellow (E172)
If you are allergic to any of the ingredients of pantoprazole 20mg tablets or medicines containing any proton pump inhibitors, or taking medicine with which pantoprazole may influence the effectiveness of, or unsure at all, speak to your doctor before taking these tablets. The colouring agent Ponceau 4R aluminium lake (E124) may cause allergic reaction. If you are taking any medication at all, even non-prescription medication, tell you doctor before taking Pantoprazole 20mg tablets.
If you lose a lot of weight for no reason, have problems swallowing, get stomach pain or indigestion, repeated vomiting, vomiting blood, look pale and feel weak, pass black stools (blood-stained faeces) have severe liver problems, have severe or persistent diarrhoea, then talk to your doctor straight away.
Pantoprazole 20mg tablets can, like any medication, cause side effects but not everyone will be affected. The following side effects are rare but serious and if any of them are noticed, stop taking Pantoprazole 20mg tablets and immediately contact your doctor. If you have severe liver problems, if you continuously need to take medicines called NSAIDs, if you have reduced body stores or risk factors for reduced vitamin B12. If you take any medicine containing atazanavir (for the treatment of HIV-infection) ask your doctor for advice. Pantoprazole also alleviates the symptoms of cancer and could cause delay in diagnosing it, so if your symptoms continue in spite of treatment, ask your doctor for advice. Your doctor will monitor you regularly if you take Pantoprazole 20mg for a long term – longer than one year.
Pantoprazole may influence the effectiveness of other medicines so tell your doctor if you are taking ketoconazole, itrazonazole, posaconazole, erlotinib, Warfarin, phenprocoumon, or Methotrexate. If you think you may be pregnant or planning to have a baby, or breast-feeding, ask your doctor for advice before taking Pantoprazole. If you experience side effects like dizziness or disturbed vision, you should not drive or operate machines.
If you experience any of the following side effects, stop taking these tablets and tell your doctor immediately: serious allergic reactions such as swelling of the tongue/throat/face, difficulty in swallowing, breathing, hives, dizziness with very fast heartbeat and heavy sweating. Serious skin conditions such as blistering of the skin and rapid deterioration of your general condition, bleeding of eyes, nose, mouth, lips or genitals, or sensitivity to light. Yellowing of the skin or whites of the eyes, fever, rash or enlarged kidneys, feeling weak, exhausted or generally unwell, any sleep disorders. Taking Pantoprazole 20mg or any other proton pump inhibitor especially over a period of more than one year may slightly increase the risk of fracture in the wrist, hip or spine. Tell your doctor if you have osteoporosis or if you are taking corticosteroids. If you experience distortion of complete lack of taste, blurred vision, pain in the joints, muscle pains, raised temperature, depression, or breast enlargement in males, disorientation, hallucinations, confusion or decreased sodium levels in the blood. If Pantoprazole 20mg is taken for more than three months there is a possibility that the levels of magnesium in the blood may fall and this may be seen as involuntary muscle contractions, fatigue, disorientation, convulsions, dizziness, or increased heart rate. Low levels of magnesium can also lead to a reduction in calcium or potassium levels in the blood and your doctor may decide to monitor your blood to check the levels.
Rare side effects may be an increase in liver enzymes, bilirubin, increased fats in the blood, a sharp drop in circulating granular white blood cells which is associated with high fever. A reduction in the number of blood platelets which may cause bleeding or bruising more than is normal, coexisting abnormal reduction in the number of red and white blood cells. Any side effects at all must be reported to your pharmacist or doctor as soon as possible.
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