Each vial of lyophilised product contains highly purified menotrophin (human menopausal gonadotrophin, HMG) corresponding to 1200IU human follicle stimulating hormone (FSH) and 1200IU human luteinising hormone (LH) activity.
Human Chorionic Gonadotrophin (hCG), a naturally occurring hormone in postmenopausal urine, is present in MENOPUR and contributes to the overall luteinizing hormone activity.
~~The powder must be reconstituted with the diluent prior to use.
Attach the reconstitution needle to the pre-filled syringe. Inject the total contents of the solvent into the vial containing the powder. The powder should dissolve quickly to a clear solution. If not, roll the vial gently between the hands until the solution is clear. Vigorous shaking should be avoided.
The reconstituted solution should not be administered if it contains particles or is not clear.
The administration syringes are graduated in FSH/LH units from 37.5 – 600 IU and supplied with needles in the Menopur multidose carton. Draw up the exact prescribed dose of reconstituted solution from the vial using one of the disposable syringes provided for injection and administer the dose immediately. Discard the syringe after use.
Each reconstituted vial should be for individual patient use only.
Any unused product or waste material should be disposed in accordance with local requirements
~~6.1 List of excipients
Sodium phosphate dibasic heptahydrate
Phosphoric acid (concentrated) for pH adjustment
Water for injection