Malarone Paediatric tablets should be taken with food or a milky drink, where possible. The tablets should be swallowed whole. However, for children who may find them difficult to swallow, they can be crushed just before being taken and mixed with food or a milky drink. It is best to take Malarone Paediatric at the same time each day.

The recommended dose to prevent malaria depends on your child’s weight.

11-20 kg - 1 tablet once a day

21-30 kg - 2 tablets once a day (as a single dose)

31-40 kg - 3 tablets once a day (as a single dose)

•ƒStart giving Paediatric Malarone 1 to 2 days before travelling to an area which has malaria
•ƒContinue giving it every day during the stay
•ƒContinue giving it for another 7 days after your return to a malaria-free area.
•For maximum protection your child must take the full course of treatment. 4

The recommended dose to treat malaria depends on your child’s weight.

5-8 kg - 2 tablets once a day for 3 days

9–10 kg - 3 tablets once a day for 3 days

Always give this medicine exactly as the  doctor or pharmacist tells you.

Active ingredients are: 62.5 mg of atovaquone and 25 mg of proguanil hydrochloride in each

tablet. Other ingredients are:

Tablet core: poloxamer 188, microcrystalline cellulose, hydroxypropyl cellulose, povidone K30, sodium starch glycollate (Type A), magnesium stearate.
Tablet coating: hypromellose, titanium dioxide (E171), iron oxide red (E172), macrogol 400 and polyethylene glycol 8000 (See section 2).

Tell your doctor if your child might be allergic to any of these ingredients before taking Malarone Paediatric

Do not take Malarone Paediatric if the child:

• is allergic to atovaquone, proguanil hydrochloride or any of the other ingredients (listed under Ingredients).

Take special care with Malarone Paediatric tablets - talk to your doctor or pharmacist before you give Malarone Paediatric to your child if:

•ƒ your child has severe kidney disease
•ƒ your child is being treated for Malaria and weighs less than 5 kg or is given Malarone Paediatric to prevent Malaria and weighs less than 11 kg

Tell your doctor or pharmacist if the child is taking, has recently taken, or might take any other

medicines (including medicines bought without a prescription):

•ƒ metoclopramide, used to treat nausea and vomiting
•ƒ the antibiotics, tetracycline, rifampicin and rifabutin
•ƒ efavirenz or certain highly active protease-inhibitors used to treat HIV
•ƒ warfarin and other medicines that stop blood clotting
•ƒ etoposide used to treat cancer