•Used for the prevention of malaria for children weighing between 11kg and 40kg
•Used to treat malaria in children weighing between 5kg and <11kg
•Malarone Paediatric tablets prevent malaria by killing the parasite that is passed on by the bite of an infected mosquito
•Contains two active ingredients, atovaquone and proguanil hydrochloride
Paediatric Malarone has two uses:
•ƒ to prevent malaria (for children weighing between 11 kg and 40 kg)
•ƒ to treat malaria (for children weighing between 5 kg and <11 kg).
Although this medicine is usually used for children and teenagers, it can also be prescribed for adults weighing less than 40 kg.
Malarone Paediatric belongs to a group of medicines called anti-malarials. It contains two active ingredients, atovaquone and proguanil hydrochloride. It is used to prevent and treat malaria in children.
Malaria is spread by the bite of an infected mosquito, which passes the malaria parasite (Plasmodium falciparum) into the bloodstream. Malarone Paediatric prevents malaria by killing this parasite. For those already infected with malaria, Malarone Paediatric also kills these parasites.
People of any age can get malaria. It is a serious disease, but is preventable.
As well as taking Malarone Paediatric tablets, it is very important to take steps to avoid mosquito bites:
•ƒUse insect repellent on exposed areas of the skin
•ƒCovers most of the body at sunset, as this is the time when mosquitoes are most active
•ƒSleep in a screened room or under a mosquito net impregnated with insecticide
•ƒMake sure to close all windows and doors at sunset, if they are not screened
•ƒUse insecticides, such as spray, plug-ins and mats to clear a room of insects and/or to deter mosquitoes from entering the room.
Malarone Paediatric tablets should be taken with food or a milky drink, where possible. The tablets should be swallowed whole. However, for children who may find them difficult to swallow, they can be crushed just before being taken and mixed with food or a milky drink. It is best to take Malarone Paediatric at the same time each day.
The recommended dose to prevent malaria depends on your child’s weight.
11-20 kg - 1 tablet once a day
21-30 kg - 2 tablets once a day (as a single dose)
31-40 kg - 3 tablets once a day (as a single dose)
•ƒStart giving Paediatric Malarone 1 to 2 days before travelling to an area which has malaria
•ƒContinue giving it every day during the stay
•ƒContinue giving it for another 7 days after your return to a malaria-free area.
•For maximum protection your child must take the full course of treatment. 4
The recommended dose to treat malaria depends on your child’s weight.
5-8 kg - 2 tablets once a day for 3 days
9–10 kg - 3 tablets once a day for 3 days
Always give this medicine exactly as the doctor or pharmacist tells you.
Active ingredients are: 62.5 mg of atovaquone and 25 mg of proguanil hydrochloride in each
tablet. Other ingredients are:
Tablet core: poloxamer 188, microcrystalline cellulose, hydroxypropyl cellulose, povidone K30, sodium starch glycollate (Type A), magnesium stearate.
Tablet coating: hypromellose, titanium dioxide (E171), iron oxide red (E172), macrogol 400 and polyethylene glycol 8000 (See section 2).
Tell your doctor if your child might be allergic to any of these ingredients before taking Malarone Paediatric
Do not take Malarone Paediatric if the child:
• is allergic to atovaquone, proguanil hydrochloride or any of the other ingredients (listed under Ingredients).
Take special care with Malarone Paediatric tablets - talk to your doctor or pharmacist before you give Malarone Paediatric to your child if:
•ƒ your child has severe kidney disease
•ƒ your child is being treated for Malaria and weighs less than 5 kg or is given Malarone Paediatric to prevent Malaria and weighs less than 11 kg
Tell your doctor or pharmacist if the child is taking, has recently taken, or might take any other
medicines (including medicines bought without a prescription):
•ƒ metoclopramide, used to treat nausea and vomiting
•ƒ the antibiotics, tetracycline, rifampicin and rifabutin
•ƒ efavirenz or certain highly active protease-inhibitors used to treat HIV
•ƒ warfarin and other medicines that stop blood clotting
•ƒ etoposide used to treat cancer
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