Estriol 1mg Cream

What is Estriol Cream?

Estriol Cream is a first-line treatment designed to help women and people assigned female at birth who are peri- or postmenopausal and experiencing symptoms like vaginal dryness, itching, or discomfort during sex. It contains a gentle form of oestrogen that works locally to ease these symptoms.

Active Ingredient

• Estriol 1mg per gram

How It Works

The natural decline in oestrogen during menopause or after ovary removal can cause vaginal tissues to become thin, dry, and sore [1]. Estriol Cream delivers oestrogen directly to the affected area. It can be applied inside the vagina or to the vulval and perianal regions. This helps rebuild natural moisture, reduce irritation, and improve comfort during sex.

Typical Results

Most women feel relief within 1–2 weeks. After 3–4 weeks of regular use, many report significantly less dryness and discomfort. After 4 weeks, most people can reduce their dose and still control these symptoms.

Key Benefits

• Works exactly where it’s needed with very little hormone entering the rest of the body
• Helps soothe dryness, itching, and discomfort
• Supports healthy vaginal tissues and improves comfort during sex
• Simple and easy to use at home
• Usually used twice a week after the first month or so

Available Dosages and Strengths

Estriol Cream is a white cream, available in a 15g tube with an applicator. Each tube provides approximately 15 to 30 doses depending on frequency of use. The cream contains 1mg of estriol per gram.

For more detailed information, see the Directions for Use section and always read the Patient Information Leaflet included with your medication.

What is Estriol Cream and what does it do?

Estriol Cream is a local hormone treatment used to relieve vaginal symptoms caused by reduced oestrogen levels during and after menopause. These can include dryness, soreness, itching, and pain during sex.

Unlike systemic HRT, Estriol Cream works directly at the site of symptoms.

How does Estriol Cream work?

Estriol is a naturally occurring oestrogen. When applied inside the vagina, it binds to local cells, helping tissues regain thickness, strength, and natural moisture. This restores balance, reduces irritation, and helps protect against infections.

What to expect when starting treatment

• Weeks 1–2: Dryness and itching begin to ease. Sex may become more comfortable. Some mild side effects (e.g., discharge or irritation) may occur but usually settle.
• Weeks 3–4: Vaginal tissues become stronger and better hydrated. Discomfort typically reduces further.
• Week 5 and beyond: You may switch to a maintenance schedule of a couple of doses per week.