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Sildenafil Tablets (25mg, 50mg,100mg)

Sildenafil Tablets (25mg, 50mg,100mg)

£ 5.89 (£1.47 per tablet)

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Buy Sildenafil Online in the UK

Sildenafil is a prescription-only medicine, used to treat men who have erectile dysfunction (also called sexual impotence). Sildenafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works.

Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. By controlling the enzyme, Sildenafil helps to maintain an erection after the penis is stroked. Without physical action to the penis, such as that occurring during sexual intercourse, Sildenafil will not work to cause an erection.

Sildenafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension. This is a type of high blood pressure that occurs between the heart and the lungs. When hypertension occurs in the lungs, the heart must work harder to pump enough blood through the lungs. Sildenafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart. (1)

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For oral use and use as directed by your doctor. 
Use in adults and elderly: The recommended dose is 50 mg taken as needed approximately one hour before sexual activity. Based on efficacy and toleration, the dose may be increased to 75 mg or 100 mg, or decreased to 25 mg. The maximum recommended dose is 100 mg. The maximum recommended dosing frequency is once per day. Sildenafil cannot be used by persons below the age of 18 years of age.

Side Effects of Sildenafil

With any medication you take, there is always a risk of side effects. Some are more common than others, and often side effects may subside with the regular usage of the medicine. If the side effects do not subside, you should report them to us, or your GP.

Common Side Effects

  • Headaches
  • Flushing
  • Runny/stuffed nose
  • Upset stomach
  • Nausea
  • Red and/or warm skin
  • Dizziness
  • Diarrhoea
  • Nose-bleeds
  • Muscle pain/Back Pain

The side effects listed below are more serious, and you should stop taking Sildenafil, and report these to your GP immediately.

  • An erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, seek medical help immediately. Priapism can permanently damage your penis. 
  • Sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking Sildenafil and call your healthcare provider right away if you have sudden vision loss in one or both eyes. 
  • Sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. If you experience these symptoms, stop taking Sildenafil and contact a doctor right away.

For a full list of side effects, please read the patient information leaflet.

Frequently Asked Questions

How long does Sildenafil last?

It is quite short-acting and lasts about 4 hours. However, in some men, the effects could last as long as 10 hours. 

What is Sildenafil used for?

Sildenafil is used for the treatment of erectile dysfunction (ED). The medication contains an enzyme called phosphodiesterase type-5 from working too quickly. With sexual stimulation, it helps the user to get and maintain an erection.

How much Sildenafil is too much?

You should not take more than your recommended dose of Sildenafil. If you take too much Sildenafil this can cause severe side effects such as a persistent and painful erection. 

How long does Sildenafil take to work?

Sildenafil is an effective drug for Erectile Dysfunction (ED) and starts to work as quickly as 12 minutes in some men, with a considerable proportion feeling the effects by 30 minutes, and the majority by 45 minutes.  Within 24 hours the medication is at very low or undetectable levels in the body. 

Is it ok to take 100mg of Sildenafil?

It is recommended that 50mg tablets are tried first, if these tablets are not giving the desired result then you could try the 100mg tablets. There isn’t much difference between 100mg and 50mg Sildenafil tablets, however, within clinical trials, the higher dosage was 82% effective compared to the lower dose at 74% effective. 
The effects of Sildenafil 100mg do not last longer than the 50mg tablets although they tend to be stronger. 

What is Sildenafil prescribed for?

If you suffer from issues with male sexual function (impotence or erectile dysfunction-ED) you can utilise Sildenafil. In conjunction with sexual stimulation, Sildenafil helps a man get and maintain an erection by boosting blood flow to the penis. This medication does not offer protection from STDs (such as HIV, hepatitis B, gonorrhoea, and syphilis). Use "safe sex" techniques, such as latex condoms. For more information, speak with your doctor or pharmacist. (2)

Does Sildenafil work?

It does, indeed. Several clinical investigations showed that Sildenafil works well for treating ED. Men who used the medication in these studies were better able to achieve and maintain erections that permitted successful intercourse.

Between 43% and 83% of the men who took Viagra reported better erections across all investigations. The type of ED they had and the dosage of Sildenafil they were taking affected these rates. In contrast, males who took a placebo saw improved erections in 10% to 24% of cases (no active drug). (9)

How does Sildenafil work?

Although they appear to be rather simple, erections are surprisingly intricate. Your heart, blood vessels, hormones, nerves, and even your mood work in harmony to get an erection.

Chemicals in the body cause the penis' tissues to relax during an erection. As a result, blood that is flowing into the penis is obstructed (you will see significantly more blood in an erect penis than in a flaccid one). The erection eventually goes away, the blood is released, and the blood flow there returns to normal.

The way Sildenaafil works is by inhibiting PDE5, an enzyme in the body that breaks down the substances that cause erections. These compounds are not degraded when PDE5 is inhibited, which keeps tissues in the penis relaxed and blood-filled.

No, Sildenafil cannot treat ED (Erectile Dysfunction). It treats the signs of ED. Sildenafil does not treat PH either. It only aids in maintaining blood pressure in the lungs' arteries.

Can women take Sildenafil?

Sildenafil has not been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) for use in females. But it may be prescribed by your doctor for off-label uses.

For the vast majority of males, Sildenafil seems to be safe, but there is less information on its long-term safety in women. (3)

Is Sildenafil the same as Viagra?

Competitors of Pfizer frequently market Sildenafil as a little white pill rather than the "little blue pill," as Viagra is known. The pill's look has no impact on how well it functions in the body or how effective it is.

Generic Sildenafil and Viagra are both equally secure and efficient, however, there is a significant price difference between the two drugs. You can get 100mg generic Sildenafil 8 tablets for £15.23, if you purchase the 100mg Viagra 8 tablets this would cost you £59.99.

How to reduce side effects of Sildenafil?

You should speak to your doctor if you are experiencing concerning side effects when taking Sildenafil. If you are on a higher dose of Sildenafil, for example, 100mg or 50mg, you may want to decrease your dose to try and stop the side effects. If you decide this is the best course of action, consult your doctor first.

How to take Sildenafil?

Take this medication by mouth as prescribed by your doctor, typically as needed to treat erectile dysfunction (ED). Prior to engaging in sexual activity, take Sildenafil for at least 30 minutes, but no more than 4 hours (1 hour before is the most effective). Never take more than once per day. (4)

Is Sildenafil safe?

The answer is yes, Sildenafil is a safe drug when used as directed. Sildenafil is licenced for the treatment of erectile dysfunction. Do not exceed the maximum daily dose and you must consult your doctor straight away if you experience any severe side effects. 

Can I take 200 mg of Sildenafil?

No more than 100mg of Sildenafil should be taken daily according to the drug manufacturer. 

How long does 100 mg of Sildenafil last?

Sildenafil lasts for up to 4 hours after taking it. However, in some men, the effects could last up to 10 hours. 

What does Sildenafil do?

Sildenafil limits PDE enzymes' ability to degrade cyclic guanosine monophosphate. This kind of chemical relaxes smooth muscle tissue throughout the body, including the blood vessels that support the erection of the penis. By assisting the arteries in relaxing long enough to allow for easier blood filling, Sildenafil usage enhances circulation.

For the majority of users, Sildenafil enters the system swiftly and reaches its peak concentration in about an hour. Similar to other PDE5 inhibitors, Sildenafil can lower blood pressure. Ask your doctor if using Sildenafil is safe if you use blood pressure medicine or have low blood pressure frequently.

Sildenafil does not automatically cause an erection or boost sexual desire. There is still a need for sexual stimulation. Sildenafil can, however, make getting an erection easier for the majority of healthy persons. (2)

What does a Sildenafil tablet contain?

Tablet core: Calcium hydrogen phosphate anhydrous, Cellulose microcrystalline, Croscarmellose sodium, Silica colloidal anhydrous, Magnesium stearate.

Tablet coat: Lactose monohydrate, Hypromellose 15cP, Titanium dioxide (E171), Triacetin.

Is there a branded version of Sildenafil available?

To treat erectile dysfunction (ED), the brand-name medication Viagra is available only by prescription (ED). You cannot achieve or sustain an erection if you have ED. Males over the age of 18 can use Viagra for this purpose.

Viagra is available in oral tablet form. It should typically be consumed an hour before engaging in sexual activity, but it can also be consumed up to four hours prior. The strengths of Viagra are 25 mg, 50 mg, and 100 mg. (4)

Which is better: Sildenafil vs Tadalafil?

Tadalafil (Generic Cialis) lasts up to 36 hours longer than Sildenafil, it has an edge over the latter (compared with 4-5 hours for Sildenafil). This allows for more spontaneity, which is why some guys love it.

How much Sildenafil is too much?

You should not take more than your recommended dose of Sildenafil. If you take too much Sildenafil this can cause severe side effects such as a persistent and painful erection. 

Is Sildenafil the best treatment to start with?

These drugs are all roughly equally effective as one another.

It does not necessarily follow that some drugs are more potent than others just because some of the dosages for some treatments appear higher than those for other treatments.

As the dosage is increased for each of these treatments, the likelihood that it will work increases slightly, but so does the risk of negative effects. If the regular dose did not work and you did not experience any severe side effects, we advise starting with the standard amount and just increasing it if necessary. Only adjust your dosage with a doctor's guidance.

To find a tablet that works for you, you might need to try a few different brands. In no case should you use more than one erectile dysfunction medication in a 24-hour period. Additionally, without seeing a doctor, never switch medications or alter the dosage of your treatment.

Which tablet has the least side effects?

Only 2% of male users of Viagra, Cialis, or Levitra may have negative effects. The likelihood that you will experience adverse effects will also depend on the dosage of the drug you are taking.

You are less likely to experience side effects when taking smaller doses of medication. In most cases, we advise trying regular doses first to rule out any side effects before considering transitioning to reduced doses. Never alter your dosage without consulting a physician.

Which tablet works the fastest?

Out of Viagra, Cialis, and Levitra, Cialis works the quickest. Viagra and Levitra can take up to an hour to start working after you take them, whereas Cialis starts working in just 30 minutes.

Try Cialis Daily if you do not want to take a pill every time you want to have sex. Everyday use of the pill Cialis Daily gives you the ability to erect whenever you wish to engage in sexual activity.

Which tablet lasts the longest?

Of the three drugs Viagra, Cialis, and Levitra, Cialis has the longest half-life. Because Cialis can last up to 36 hours, it is commonly referred to as the "weekend pill." Levitra and Viagra have a six-hour duration.

Cialis Daily is consistently active. Cialis Daily will continue to function as long as you continue taking one tablet every day.

It does not follow that you will have an erection for that length of time just because the effects of these drugs can linger for hours. When you are aroused, these drugs can help you achieve and maintain an erection, but they do not work as effectively as they could. (1)

Is it recommended to use Sildenafil with other treatments for better results?

Take care to use the appropriate medication for yourself.

Despite having a similar mechanism of action, ED medications differ chemically from one another. This may have an impact on how they function, how long it takes for them to take action, and which side effects you experience.

Any health issues you may have as well as any other medications you take should be discussed with your doctor. It will aid your doctor in determining which ED medication will benefit you the most.

Give it time to work. You must wait a bit for the majority of ED medications to begin to take effect. The length depends on the substance. 

The effects of Viagra and Levitra start to take effect after around 30 minutes and last for roughly 4 hours.

Cialis should be taken at least 2 hours prior to your intended sexual activity. After taking it, the effects could last for up to 36 hours.

To determine whether you need to up your dose, consult your doctor.

You could need to take a higher dose if the current dosage you are using does not give you an erection. However, do not attempt this alone. If you think you would benefit from taking more medicine, discuss it with your doctor.

Take it slow.

You have time on your side. An erection cannot be expected to occur immediately after using an ED medication. Nitric oxide, a substance your body naturally produces, and which relaxes the muscles in your penis, is enhanced by the drugs. This enhances blood flow and facilitates erection.

But you must be sexually stimulated for the medications to operate. Therefore, do not haste. Give yourself some time to settle in. To get turned on, make use of all of your senses.

What is the maximum Sildenafil dosage per day?

The strengths of Sildenafil pills used to treat erectile dysfunction range from 25 mg to 100 mg.

When needed, a 50 mg dose is typical. Take it no more than once per day.

Depending on the outcome, the dose can be either increased to 100 mg or decreased to 25 mg.

What is the best time of the day to take Sildenafil?

Use as and when necessary; it doesn't matter the time of day.

What happens if I miss a dose of Sildenafil?

Never take two doses at once. Never take a second dose to make up for the one you missed.

Set an alarm to remind you if you frequently forget to take your medication. Asking your pharmacist for suggestions on alternative strategies to help you remember to take your medication is another option.

What happens when you stop taking Sildenafil?

There are no withdrawal symptoms related to stopping Sildenafil, however, you may struggle when trying to get an erection. Consult your doctor if you are unsure about stopping the medication.

What are the possible side effects of Sildenafil?

Bladder pain, a burning sensation in the chest or stomach, murky or bloody urine, more frequent urination, pain during urination, upset stomach, and tenderness in the stomach region are all possible side effects. (5)

Can Sildenafil's side effects last?

The majority of Sildenafil's adverse effects are minor and disappear soon when the pill takes effect. However, some severe adverse effects can, in rare circumstances, cause long-term issues. For instance, Viagra may prolong an erection. If left untreated, erectile dysfunction may become chronic. (6)

What are the alternatives to Sildenafil?

Tadalafil (Cialis)

The oral pill, Cialis begins to function around 30 minutes after you take it. For up to 36 hours, it can increase erectile function. The 2.5 to 5 mgme daily dose range is the recommended starting point, however, it can be changed as needed. You only take it once per day, just when necessary. Cialis may be taken with or without food.

There is also a once-daily variation. These 2.5-mg pills must be taken every day at the same time.

Vardenafil (Levitra)

A good hour before engaging in sexual activity, take Levitra. 10 mgmes is often the initial dose. Limit your intake to once per day. These oral pills can be taken with or without food.

Avanafil (Spedra)

There are 50, 100, and 200 mg tablets of Spedra available. You take it once daily, but no more than 15 to 30 minutes before engaging in sexual activity. It may be consumed with or without meals. (7)

What is the difference between Sildenafil and Tadalafil?

PDE5 inhibitors like Cialis and Viagra are both prescribed to treat erectile dysfunction (ED).

Both only function when a man is stimulated sexually.

Viagra only lasts 4 to 5 hours while Cialis lasts about 36 hours.

Cialis' activity is unaffected by food, whereas food can make Viagra less effective.

BPH (Benign Prostatic Hyperplasia) can be effectively treated with Cialis, which can be taken once daily at a lower dosage (BPH).

Men who have liver or renal issues may need to take Cialis at a lower dosage, and the chance of interactions may be greater than with Viagra. (8)

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Sildenafil Tablets (25mg, 50mg,100mg) - Patient Information Leaflet

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References

  1. Mayo Clinic - Sildenafil oral route
  2. Web MD - Sildenafil uses
  3. Healthline - Does Viagra have an effect on women
  4. Healthline - Generic Viagra how does it work?
  5. NHS - How and when to take Sildenafil
  6. Healthline - Viagra side effects
  7. Healthline - Viagra alternatives approved by doctors
  8. Drugs.com- Cialis vs Viagra - What's the difference between them? - Reviewed 01.04.22
  9. Medical News Today - Viagra (Sildenafil)

Related Erectile Dysfunction Treatment Information

  1. Cialis Together available over the counter without a prescription
  2. Is BlueChew available in the UK? and the alternatives
  3. When to take Cialis for the best results and maximum effect
  4. Can tadalafil and alcohol be taken together?
  5. How to stay harder for longer and maintain an erection

More ...

Authored on 01 September 2022

Stuart Gale

Stuart Gale - BSc (Hons) MRPharmS

Pharmacist and Owner

GPhC Number: 2039889

Reviewed on 07 September 2022

Robert Bradshaw

Robert Bradshaw - MRPharms BSc(Hons) Pharmacy

Superintendent Pharmacist

GPhC Number: 2036118

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