Wegovy Injection (0.25mg + 0.5mg) Starter Pack for Weight Loss

Before injecting:

• Check the expiration date, dose amount and do not use the pen if it has been frozen, is cloudy or if there is discolouration.

• Pull off the pen cap and attach a new needle (NovoFine Plus, NovoFine, or NovoTwist, up to 8mm) before each injection.

• The needle is covered by two caps. Remove both caps. Keep the first cap which you will need later and dispose of the second.

• Check the flow before injection (see patient information leaflet for how to do this properly)

• Turn the dose selector until the dose counter stops and shows your prescribed dose.

• Choose your injection site– upper arms, stomach or upper legs. Avoid 5cm around your belly button.

During injection:

• Insert the needle into your skin and make sure you can see the dose counter.

• Hold down the dose button until the dose counter shows 0.

• You may hear or feel a click when it returns to 0.

• Remove the needle from your skin. Do not remove it before a full dose has been administered.

After injection:

• Reattach the needle cap that you saved when attaching the needle.

• Unscrew the needle and dispose of it in your sharps bin.

• Put the main pen cap back and store it out of sunlight.

Please read the full Patient Information Leaflet that is provided in the Wegovy injection box before injecting.

Delivery and storage of Wegovy injections

As of April 2026, Wegovy pens can be delivered without ice packs at a temperature below 30°C for up to 48 hours (1). Once your pens arrive, you should store them in the fridge (between 2-8°C). Wegovy FlexTouch pens can be stored at room temperature (below 30°C) for 6 weeks (1). Always keep it out of direct sunlight and direct heat sources.

As FlexTouch pens can only be stored for 6 weeks at room temperature, you should store your 0.5mg pen in the fridge until you have completed your first month on the 0.25mg and are ready to increase your dose to 0.5mg.

Common (Between 1% and 10% of patients):

• Nausea

• Vomiting

• Diarrhoea

• Constipation

• Stomach pain

• Headache

• Feeling weak or tired

• Indigestion, bloating, burping, flatulence

• Gastritis (stomach ache, nausea or vomiting)

• Reflux or heartburn

• Gallstones

• Hair loss (reported more frequently at 7.2mg)

• Injection site reactions

• Change in taste

• Change in skin sensation (more frequent at 7.2mg)

• Low blood sugar (in patients with diabetes)

• Complications of diabetic eye disease (diabetic retinopathy, in patients with diabetes) (1, 2)

Uncommon (Between 0.1% and 1% of patients):

• Feeling dizzy

• Acute pancreatitis, reported in 0.2% of patients on semaglutide 2.4mg versus under 0.1% on placebo in phase 3a trials

• Kidney or bladder stones (1, 2)

• Increased heart rate

• Delayed gastric emptying

• Serious, requiring urgent medical attention - Rare (between 0.01% and 0.1% of patients)

• Acute pancreatitis: severe, persistent stomach or back pain, with or without nausea and vomiting. This is life-threatening and needs immediate medical help.

• Severe allergic reaction (anaphylaxis, angioedema): breathing difficulty, swelling of face/lips/tongue/throat, fast heartbeat, dizziness or feeling faint.

• Hip fracture.

• Sudden or worsening vision loss.

• Bowel obstruction: severe constipation with stomach ache, bloating and vomiting.

• Gallstones progressing to cholecystitis, reported in 0.6% of patients on semaglutide 2.4mg (1, 2)

You shouldn't use Wegovy if you are allergic to Semaglutide or any of the other ingredients in the pen (disodium phosphate dihydrate, propylene glycol, phenol, sodium hydroxide or hydrochloric acid, water for injection).

You also shouldn't use Wegovy if you are pregnant, planning to become pregnant, or breastfeeding. If you're planning to conceive, you must stop taking Wegovy at least 2 months beforehand.

Any other health conditions that may require caution when taking Wegovy or specialist review will always be decided with your prescriber.