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Orlistat 120mg Weight Loss Capsules

Orlistat 120mg Weight Loss Capsules

£ 17.49 (0.42p per capsule)

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120mg
42 capsules£17.49
84 capsules£34.99
168 capsules£68.94
252 capsules£99.94
  • Product Information
  • Reviews
  • Directions for Use
  • Side Effects

Buy Orlistat Online in the UK 

What is orlistat? 

Sometimes, the body needs a helping hand to shed weight and in cases where people have tried and failed to lose weight through diet alone, medication can help.  

Orlistat 120mg capsules, often known by the brand name Xenical, is a medicine used to treat obesity. 

Orlistat suppresses stomach and pancreatic lipases in a reversible manner. its main function is to restrict fat absorption from the human diet by acting as a lipase inhibitor which in trials has been shown to improve lipid metabolism in obese individuals, therefore lowering caloric intake. 

In more simple terms, orlistat is a fat binder medication that accomplishes precisely what it states on the label. 

When you take orlistat capsules, the active ingredient binds to the fat in your meals, preventing it from being digested and passing through your body. 

Because extra fat is excreted in your poo, one of the most common side effects of the medication is oily or fatty poo. 

How does orlistat work? 

When combined with a balanced diet, orlistat can help boost weight loss for people with a BMI of over 30, or those with a BMI of 28 - 30 and who suffer from other risk factors, such as diabetes. 

Orlistat works in the following ways to aid weight loss: 

  • Prevents your body from absorbing fat from the food you eat. 
  • Help keep you from gaining the weight you have lost. 

Does orlistat work?  

Yes, orlistat has been proven to be an effective weight loss aid. According to multiple studies, it resulted in significantly more weight loss than placebo when paired with food and behaviour change and generated modest improvements in lipid profile, glycaemic management, and blood pressure. (7) 

It has been proven to prevent the absorption of nearly one-third of dietary fat. 

Does orlistat burn existing fat?  

Orlistat does not affect your existing fat cells; instead, it binds to the fat in your food. 

This reduces your calorie intake, allowing your body to use the fat you've built up for energy. 

When you consume more calories than your body requires, they are stored as fat for later use, which is why you gain weight in the first place. 

Learn more about calorie deficit here.

You can lose weight slowly and sustainably by forcing your body to use up these fat stores by reducing your calorie intake over time. 

Does orlistat make you feel full? 

Orlistat works fully in the gastrointestinal tract and does not alter the central nervous system. If you are looking for a weight loss aid that stops you from feeling hungry or produces the feeling of fullness, you can consider Saxenda or Wegovy injections, as well as the recently introduced Mysimba tablets. 

Can you take orlistat and Saxenda together?  

Although there are no clear contraindications to using Saxenda and orlistat together, we strongly advise against it. While you may believe that using this strategy will allow you to lose weight twice as quickly, this is not the case.

Taking Saxenda and orlistat combined will not speed up your weight reduction and will increase your chances of suffering unpleasant side effects.   

Check out our blog article Saxenda vs. orlistat here.

Buying orlistat online 

Buying prescription weight loss medication from Oxford Online Pharmacy couldn’t be easier. Simply add a product to your basket before completing your online consultation.  

The Manufacturer of this product may vary. 

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How to take orlistat? 

The usual recommended dose of orlistat 120mg is to take one capsule three times a day before, during or up to one hour after each main meal. 

Avoid foods containing fat such as biscuits, chocolate and savoury snacks between meals. 

Do not chew the capsule - swallow it whole with a glass of water.  

We would always advise you to take a multivitamin preparation which should be taken at bedtime or two hours after taking orlistat. 

How long does orlistat take to work? 

When beginning orlistat, it typically takes approximately 24 - 48 hours to initiate its action. 

If the medication is taken correctly, you can expect to observe weight loss results within a few weeks of starting the treatment. 

How long does orlistat stay in your system?  

The presence of orlistat in your system is influenced by your digestive tract and bowel transit time, lasting for only 12 - 72 hours. Various sources have indicated that after discontinuing orlistat, faecal fat levels typically return to their pre-orlistat levels within 48 - 72 hours. 

Orlistat side effects 

With any medication you take, there is always a risk of side effects. Some are more common than others, and often side effects may subside with regular usage of the medicine.?If the side effects do not subside, you should report them to us, or your GP. 

Very common side effects:

  • Headache 
  • Upper respiratory tract infection 
  • Abdominal pain/discomfort 
  • Urgent or increased need to open the bowels 
  • Flatulence (wind) 
  • Flatulence (wind) with discharge 
  • Oily discharge 
  • Oily or fatty stools 
  • liquid stools 
  • Increased elimination of stools 
  • Influenza (‘flu’) 
  • Low blood sugar levels (experienced by some people with type 2 diabetes). 

Common side effects:

  • Lower respiratory tract infection 
  • Rectal pain/discomfort 
  • Soft stools 
  • Faecal incontinence (inability to control your bowel movements) 
  • Bloating (experienced by some people with type 2 diabetes) 
  • Tooth/gum disorder 
  • Urinary tract infection 
  • Irregularity of menstrual cycle 
  • Tiredness 
  • Anxiety 

Please read the patient information leaflet for a full list of side effects. 

How long do orlistat side effects last? 

Typically, any reaction to orlistat manifests within the initial three months of usage, and approximately half of the time, any side effects experienced tend to resolve within a week.  

If you are concerned about any of the side effects that you are experiencing, please get in touch with one of our healthcare professionals who will advise you. 

Frequently Asked Questions

Can you buy orlistat over the counter?

If you wish to buy any of the non-prescription, 60mg products such as Orlos capsules or Alli capsules, you can do so quickly and easily; simply answer a brief questionnaire and the product will be added to your basket.  

If you require a product containing 120mg orlistat, you will need to complete our online doctor consultation before purchasing the product. If approved then the medication will be issued or if not, a full refund given.  

Can I get orlistat on the NHS?

Your doctor may be able to refer you to a weight loss specialist who will then decide if orlistat is a suitable treatment for you, however, the NHS has very specific guidelines they must follow, and you may find that you are not eligible for orlistat NHS. 

To read more about getting orlistat on the NHS check out our blog post here.

How to get the best results from orlistat?

Orlistat works alongside a healthy diet and exercise routine.  

A vital aspect of maintaining good health is following a well-balanced diet, which includes some fats. 

To optimise the effectiveness of orlistat and minimise the amount of undigested fat passing through your system, it is recommended to distribute your fat intake evenly among the meals you consume throughout the day. 

You can find more information on getting the best results from orlistat here.

Who shouldn’t use orlistat?

Orlistat is a great weight loss aid for many however, you must always check whether it is a safe option for you. Before using orlistat, you should always do the following: 

  • Inform the doctor of any other medicine you take. 
  • Check that you do not have allergies to any of the ingredients in the medicine. 
  • Inform your doctor of any health issues. 
  • Inform your doctor if you are pregnant or breastfeeding, you will likely be advised to not start/ or stop the treatment. 

Is orlistat safe?

Orlistat (Xenical) has been accessible as a prescription-only medication due to being approved by the MHRA (Medicines and Healthcare Products Regulatory Agency).  

Since 1998 orlistat has been a popular, well-known treatment that many rely on to help them lose weight. 

According to an evaluation of the efficacy and safety of orlistat in obese patients, orlistat is an effective and well-tolerated anti-obesity medication that can be used in conjunction with therapeutic lifestyle changes to help achieve and maintain optimum weight. (8) 

How much weight can you lose with orlistat?

If orlistat is the appropriate treatment for you, you can expect to experience a reduction of about 5% in your initial body weight within 12 weeks of commencing the treatment. 

On your next order you should provide us with your updated weights so we can check if you are on track to achieve the 5% weight loss goal and inquire about any potential side effects. 

This follow-up is crucial as it ensures that the prescribed treatment is suitable for you and provides an opportunity for you to address any inquiries you may have regarding your weight loss journey so far. 

Is orlistat good for weight loss?

Orlistat helps reduce the amount of fat absorbed in your intestines, resulting in weight loss.

Dietary fat can be consumed or stored for energy by being broken down into smaller pieces with the aid of the digestive enzyme lipase.(1)

Is orlistat harmful?

More specifically, the usage of orlistat has been linked to a number of mild-to-moderate gastrointestinal side effects, including faecal spotting, oily stools, diarrhoea, and abdominal pain.(2)

Does orlistat work without exercise?

Is orlistat effective? Studies have shown that combining orlistat with a weight-reduction diet and exercise generally leads to more weight loss than either option by itself. With the use of orlistat, some people lose 10% or more of their body weight in less than six months.(3)

How long can you stay on orlistat?

Only if you have dropped 5% of your body weight over the first three months of treatment with orlistat you should continue it.
It normally starts to impact how you absorb fat within a day or two. It's unlikely that orlistat will work as a treatment for you if you haven't lost weight after taking it for three months.(4)

Can I take one orlistat a day?

Recommended dose

One capsule (120 mg) of orlistat taken three times day is the maximum dosage. The best time to take the medication is right before, during, or up to an hour after eating. Do not take the capsule if you miss a meal for any reason.

What happens after taking orlistat?

Orlistat works by preventing the enzyme that breaks down the fat in your diet. After that, bowel movements release this undigested fat from your body. You still need to limit your overall calorie intake because orlistat does not stop the absorption of calories from sugar and other non-fat meals.(5)

Do you gain weight after stopping orlistat?

Some people who take orlistat regain the weight they have lost when they stop taking it. (6)

How long does Orlistat take to work?

Orlistat is usually taken three times a day; once with each meal that contains 1-15g of fat. It works immediately by preventing some of the fat that you have just consumed in a meal from being absorbed into your body. If taken in conjunction with a calorie-controlled diet and increased exercise, Orlistat can improve sustained weight loss. 

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Orlistat 120mg Weight Loss Capsules - Patient Information Leaflet

leaflet icon

References

  1. Healthy Weight Loss In Depth - Mayo Clinic
  2. Orlistat-associated adverse effects and drug interactions: a critical review - PubMed - Theodosios D Filippatos 1, Christos S Derdemezis, Irene F Gazi, Eleni S Nakou, Dimitri P Mikhailidis, Moses S Elisaf
  3. Weight Loss Medicine - Patient Info - Authored by Dr Laurence Knott
  4. Obesity Treatment - NHS
  5. How to use Orlistat 120 Mg Capsule Fat Absorption Decreasing Agents - WebMD
  6. Dietary advice for patients taking orlistat -NHS Department of Nutrition and Dietetics
  7.  Pharmacotherapy. Author manuscript; available in PMC 2018 Sep 19. Published in final edited form as: Pharmacotherapy. 2000 Mar; 20(3): 270–279, Orlistat, a New Lipase Inhibitor for the Management of Obesity, Dr. Amy M. Heck, Pharm.D., Dr. Jack A. Yanovski, M.D., Ph.D., and Dr. Karim Anton Calis, Pharm.D., M.P.H., FASHP
  8. Indian J Endocrinol Metab. 2011 Apr-Jun; 15(2): 99–104., doi: 10.4103/2230-8210.81938, Evaluation of efficacy and safety of orlistat in obese patients, Suyog S. Jain, Sunita J. Ramanand, Jaiprakash B. Ramanand,1 Pramod B. Akat, Milind H. Patwardhan,2 and Sachin R. Joshi

Related Weight Loss Information

  1. Wegovy patient support
  2. How much does Saxenda cost in the UK?
  3. Switching from Saxenda to Wegovy
  4. When is Wegovy UK release date?
  5. Can you drink alcohol on Wegovy?

More ...

Authored on 26 July 2023

Robert Bradshaw

Robert Bradshaw - MRPharms BSc(Hons) Pharmacy

Superintendent Pharmacist

GPhC Number: 2036118

Reviewed on 26 July 2023

Stuart Gale

Stuart Gale - BSc (Hons) MRPharmS

Pharmacist and Owner

GPhC Number: 2039889

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