Evorel Sequi (Estradiol / Norethisterone) 8 Patches

Evorel Sequi (Estradiol / Norethisterone) Patches

£28.99 (£3.62 per patches)

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	100N/A
8 patches	£28.99
24 patches	£55.95

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Evorel Sequi (Estradiol/Norethisterone) Patch is a Hormone Replacement Therapy (HRT). It contains two female hormones an Oestrogen-Estradiol and a Progestogen-Norethisterone. It is used for the symptoms of menopause and to prevent osteoporosis. It is only used in women who still have a womb.

Evorel Sequi is packaged in a 'Memory pack'. You can use this to help you keep track of when to replace your patches. Eight patches are included in each box.

Four "Evorel 50" patches with the CE50 stamp (containing estradiol only)
Four "Evorel Conti" patches with CEN1 markings (containing estradiol and norethisterone)

In each patch, the hormones are spread equally. They enter your body slowly through the skin.

What Evorel Sequi is used for?

Evorel Sequi is used to treat the following conditions:

Only women who still have a womb can use them. It is appropriate for women who have had menopause (postmenopausal) or are around the time of menopause (perimenopausal).
To protect women who have experienced menopause and are at a higher risk of developing bone problems from osteoporosis (frail bones). Only when other osteoporosis medications have been tried and failed is Evorel Sequi prescribed.

What is menopause?

All throughout their adult lives, women's ovaries produce oestrogen hormones. These hormones play an essential role in menstrual cycle regulation and sexual development.

When the amount of hormones released by the ovaries decreases, menopause occurs. This happens gradually. The amount of oestrogen can fluctuate during this time.

This may result in:

Night sweats
Mood swings
Hot flushes
Painful or uncomfortable sex
Vaginal issues include dryness or irritation

If you have had your ovaries removed through surgery, you can experience the same symptoms.

How Evorel Sequi works

Evorel Sequi is a type of HRT called "continuous sequential." This is due to the sequential usage of two hormones:

Estradiol is administered alone for two weeks, followed by two weeks of combined use of estradiol and norethisterone. The oestrogen that is typically released by the ovaries is replaced by Evorel Sequi patches. On the other hand, taking oestrogen frequently may cause the lining of your womb to thicken and accumulate.

This means that a progestogen hormone must be added to oestrogen in order to shed the uterine lining and prevent complications. This progestogen is present in Evorel Conti patches worn during weeks three and four.

There will likely be a "withdrawal bleed" as the womb's lining sheds. It will be similar to getting your period every month. Before you finish one Evorel Sequi pack in week 4, the withdrawal bleed will begin.

Evorel Sequi is not a contraceptive. You might still need to use supplementary contraception to avoid conception if it has been less than 12 months since your last period or if you are under 50 years old. Talk to your doctor for suggestions.

Evorel Sequi (Estradiol / Norethisterone) Patches reviews

How to use Evorel Sequi (Estradiol / Norethisterone) Patches

Always use this medicine exactly as instructed by your doctor. Please read the patient information leaflet before use.

The patches need to be changed twice a week, your patch must be changed on the same two days every week. You must use the patches in the right order. Week 1 and 2 use the four Evorel 50 patches one at a time. Weeks 3 and 4 use the four Evorel Conti patches one at a time. As soon as you remove your fourth Evorel 50 patch, replace it with the first Evorel Conti patch.

The patch is to be applied to a hairless area of skin below the waist, ideally the thigh or bottom.

Do not apply the patch to the following:

On or near the breasts
On top of cuts, spots or anywhere the skin is irritated
On the same area of skin twice in a row
Do not use cream, moisturizer or talc before applying the patch
Do not wear a patch under elasticated areas or a tight waistband

Follow the instruction in the patient leaflet on how to apply and remove the patch.

Side effects of Evorel Sequi (Estradiol / Norethisterone) Patches

Please read the patient information leaflet before starting this medication.

If you experience any of the side effects listed below or not listed in the leaflet please consult your doctor or pharmacist.

Very common (affects more than 1 in 10 people)

Irritated, itchy, red skin where the patch is applied

Common (affects less than 1 in 10 people)

Feeling depressed or nervous
Pain including pain in the back, muscles, joints
Inappropriate signs of emotion
Feeling sick (nausea), or having stomach pain wind or other stomach upsets
Diarrhoea
Feeling generally unwell
Being unable to sleep
Headache
Itchy skin or red rash
Heavy vaginal bleeding, painful periods
Water retention or build-up of fluid under the skin (oedema)
Breast pain
Weight gain

Uncommon (affects less than 1 in 100 people)

Concentration problems
Breast lumps (non-cancerous)
Fuller breasts
Irregular vaginal bleeding
Feeling dizzy
A fungal infection called thrush
Allergic reaction (hypersensitivity)
Mood swings
Bloated feeling
Gallstones
Feeling tired
Being aware of your heartbeat (palpitations)
Numb or tingling hands or feet, less skin sensitivity
More or less interest in sex than usual
Thickening of the lining of the womb
Frequency not known
Puffy skin where the patch is applied
Swelling of the hands and feet (peripheral oedema)

Please give your doctor a full medical history to ensure the appropriate medication is prescribed.

Keep out of reach and sight of children. Do not store above 25 degrees Celcius.

Frequently Asked Questions

: The oestrogen that is typically secreted by the ovaries is replaced by Evorel Sequi patches. However, taking oestrogen frequently may cause the lining of your womb to thicken and accumulate. There will likely be a "withdrawal bleed" as the womb's lining sheds. It will be similar to getting your period every month.
: A variety of menopausal symptoms, including extreme physical ones like hot flushes, insomnia, night sweats, osteoporosis, and vaginal dryness, as well as unpleasant psychological ones like mood swings, anger, and sadness, can be effectively treated with Evorel Sequi.
: Yes. This is due to the fact that the Evorel Sequi patches contain oestrogen, which might cause the lining of your womb to thicken. When progesterone patches are applied, this is broken down, resulting in a bleeding phase similar to a withdrawal bleed.
: You should apply one patch twice a week to a clean, dry, intact, non-irritated area of skin below the waist, preferably on the buttock or hip. In each monthly cycle, you apply Evorel 50 patches for the first two weeks and Evorel Conti patches for the next two weeks.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Evorel Sequi (Estradiol / Norethisterone) Patches - Patient Information Leaflet

Message From Our Pharmacist

All hormone replacement therapy should be initiated after a discussion with a health care professional face to face as they will also need to take your blood pressure and weight. Blood tests may also be requested. This is followed after three months with a follow-up appointment. Online prescribing can only be done once this has happened.

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