Rimegepant a new hope for migraine sufferers

What is Vydura? 

Migraine sufferers in the UK have reason to celebrate as a groundbreaking pill promises to provide relief to around 13,000 individuals who endure severe and untreatable migraines.  

Vydura is the brand name for rimegepant (pronounced rim-edgy-pant), a new type of migraine treatment for people who experience migraines with or without aura. 

Migraine is a condition that can significantly impact the lives of those who suffer from it, affecting their ability to work, maintain relationships, and even their mental health. Rimegepant, with its cost-effective pricing and impressive results, is a ray of hope for thousands of people in the UK who have been longing for a solution to their debilitating migraines. This medication promises to be a game-changer, offering relief and improved quality of life to those in need.  

How does Vydura work? 

At the onset of a migraine, nerve cells in the brain release a substance known as calcitonin gene-related peptide (CGRP). This CGRP triggers the dilation of blood vessels in the brain, leading to inflammation. 

This inflammation can transmit pain signals to your brain. 

Elevated levels of CGRP have been demonstrated to initiate and prolong migraines. 

The active ingredient in Vydura, rimegepant, functions as a CGRP inhibitor. In other words, it can counteract the effects of CGRP. 

These CGRP inhibitors play a role in diminishing inflammation, preventing the expansion of blood vessels, and ultimately reducing the severity and frequency of migraines. 

It's worth emphasising that CGRP is only one component in the complex puzzle of migraine triggers. Migraines are multifaceted conditions influenced by various factors such as genetics, hormones, and other chemicals in the brain. 

Vydura in the news 

With articles in the Guardian, Daily Mail and BBC News, this migraine medicine has caught the attention of many people. 

Rimegepant, sold under the brand name Vydura in the UK, has garnered attention not just for its efficacy, but also for its celebrity endorsement. Reality star Khloe Kardashian, who herself suffers from migraines, publicly endorsed rimegepant, highlighting its potential to provide relief to those battling this debilitating condition. 

How much does Vydura cost? 

The cost of rimegepant, known as Nurtec in the US, starts from £54.99 at Oxford Online Pharmacy and the good news is that eligible NHS patients in England will only pay £9.65 per dose. This cost-effective option opens doors for those who have been hesitant due to financial concerns. 

Who is eligible for Vydura? 

Under the guidelines issued by the National Institute for Health and Care Excellence (Nice), rimegepant will be made available to acute migraine sufferers who have already tried at least two types of triptans without success. Triptans are a class of medications commonly prescribed for headaches or migraines. Additionally, patients who are unable to tolerate triptans or have found no relief from over-the-counter painkillers for their migraines will also be eligible for this medication. 

Does Vydura work? 

Clinical trials have demonstrated the efficacy of Vydura (rimegepant) in managing acute migraine episodes and reducing the occurrence of frequent migraines. In a study examining rimegepant as a migraine treatment, it was observed that following the administration of the medication, 59% of individuals reported relief from pain within a two-hour timeframe. 

Where to buy Vydura? 

Vydura is available to buy from Oxford Online Pharmacy. Once our GMC registered doctors approve your suitability this medicine could be sent out for delivery as fast as the next day.  

*Prices are as of 11.10.23 and are subject to change.