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Aklief (trifarotene) 75g cream for acne

Aklief (trifarotene) 75g cream for acne

£ 49.99

Buy Aklief Cream Online in the UK

Where can I buy Aklief cream?

Aklief cream is available at Oxford Online Pharmacy with a private prescription. With the completion of our online consultation, our GMC-registered doctors will assess your suitability for treatment and then issue a free-of-charge private acne cream prescription, you will just need to pay for the medicine.

To buy Aklief Cream from Oxford Online Pharmacy, you can follow these 3 steps:

  1. Complete a short consultation
    The first step is to complete a short consultation so our online doctors can determine whether this is the right treatment for you. Our GMC-registered doctors will then review your completed consultation.
     
  2. Choose your medication
    You can now choose your medication, this could be the medication you are currently on or a new medication, using your consultation our doctors will make sure that your chosen medicine is the right treatment for you. If it is, they may provide some extra notes regarding directions of use for this medication. However, if they believe your chosen medicine is not the most suitable treatment, they will make recommendations regarding what sort of treatment would be better for your needs.
     
  3. Fast, discreet, shipping
    When you have finished the steps above your medication will be scheduled for delivery to the address of your choosing (you will do this when you pay).We will make sure that you receive your medication quickly and discreetly – we always use discreet labels and packaging so no one will know what’s inside.

What is Aklief cream?

Aklief cream is a topical treatment for acne, containing the active ingredient trifarotene, which is part of a class of medications known as retinoids, Aklief is a topical retinoid cream used to treat Acne on the face or upper body in patients with several whiteheads, blackheads or inflammatory pimples. The results of this treatment may be seen in as little as 2 weeks.

What does Aklief cream do?

Aklief Cream contains the active ingredient trifarotene which is also known as a retinoid, this chemical helps the skin replace old skin cells at a faster rate, exfoliating away the old cells which in turn will prevent any new acne from forming.

By encouraging the new cells and preventing hair follicle blockage, topical retinoids such as Aklief prescription acne cream will also work to reduce inflammation and control the formation of acne lesions such as pimples, whiteheads, and blackheads. It is important to note that Aklief is intended for use on the face and upper body and can be used along with a oral or topical antibiotic treatment.

In more than one recent studies, it was established that improvements in body and facial acne were seen in patients who were using Aklief cream for acne. (2)

Acne Types, Causes and Symptoms

According to research, acne affects 9.4% of the global population, making it the eighth most frequent disease in the world. Effecting up to 85% of adolescents, and while most people think that it's only effects teenagers, its also seen in adults yoo (1) 

Acne is caused when the skin produces too much sebum, which will clog the hair follicles with dead skin cells. In turn this will cause blackheads and whiteheads to form on the skin, if they then get infected this will cause larger and more painful lumps known as pustules or cysts.

Not only does acne cause physical symptoms but many people will suffer low self-esteem and even depression as a result.

Alternatives to Aklief

There are plenty of acne treatment alternatives available at Oxford Online Pharmacy. From oral antibiotic treatments such as Doxycycline 50mg Capsules or Lymecycline 408mg Capsules to topical acne creams, including, Duac Daily (Clindamycin + Benzoyl Peroxide) or Epiduo

Taking some of the most popular acne medicines we will explore and compare the differences against Aklief:

Aklief Cream vs Lymecycline Capsules

Other than the most obvious difference between these two medicines which is the forms, one being a cream and the other capsules. They have different functions which means they target acne in separate ways.

Aklief is a topical retinoid and Lymecycline capsules are an oral antibiotic. Topical retinoids work by exfoliating the dead skin cells resulting in preventing the blockage of pores, while antibiotics suppress the growth of acne and the formation of free fatty acids.

A doctor may prescribe both as a treatment and preventative, this will be assessed on whether your type of acne is suitable and how severe it is.

Aklief vs Epiduo Gel

Aklief Cream and Epiduo Gel are both retinoids, however, Aklief is the gentler of the two.

Epiduo Gel contains two active ingredients, Benzoyl Peroxide and Adapalene, the gel also includes an antibacterial medicine.

Aklief vs Differin gel

The active ingredient in Aklief is trifarotene, a retinoid cream and Differin Gel contains the active ingredient adapalene which is an anti-inflammatory.

Because retinoids like Aklief (trifarotene) cream are treat the skin and are anti-inflammatory, they are the preffered acne topical therapy. Retinoids also allow for the maintenance of clearance in comparison to Differin gel which only has anti-inflammatory properties.

Differin 45g gel is recommended for more sensitive, dry skin and can be used for normal to oily skin. It anti-inflammatory properties work by reducing the soreness and irritation caused by acne. 

Aklief vs tretinoin

So finally, what is the difference between Aklief and tretinoin? Well, unlike other generic retinoids, is well tolerated and creates less skin irritation than tretinoin and this is why it may be the choice for those with more sensitive skin. So, is Aklief stronger than tretinoin? No, tretoinoin is stronger than Aklief. With that said, Aklief is still a strong topical retinoid and can cause irritation, so those with sensitive skin or eczema-prone skin should proceed with caution.

At this time, Aklief as a branded retinoid is priced higher than tretinoin due to it being a branded product.

When it comes to sensitive skin, Aklief is usually better tolerated than tretinoin, but the two retinoids are still more similar than they are different. Both are topical retinoid therapies with the goals of treating acne and lowering inflammation.

Tretinoin is not available yet from Oxford Online Pharmacy, but you can buy Aklief cream.

FAQs

Who can use Aklief?

Aklief Cream is a prescription retinoid used to treat acne vulgaris on the skin and is available at Oxford Online Pharmacy to those over the age of 18.

Can I use Aklief cream to treat blackheads?

Aklief Cream may aid in the reduction of acne cysts, blackheads and whiteheads.

Could my acne come back after treatment with Aklief Cream?

When you stop using Aklief Cream, your acne may reappear. This does not mean the cream isn't effective. After stopping use your pores can become clogged again, causing acne to reappear. This is why it is important to follow your doctors treatment advice.

What is Trifarotene?

Trifarotene belongs to the retinoids class of medicines. It works by encouraging skin peeling, preventing new pimples from growing beneath the skin and unclogging pores. 

What is a topical retinoid cream?

Topical retinoids work by removing the dead skin cells while also increasing the creation of new skin cells. These dead skin cells and excess oil are pushed out of clogged pores by the young cells. Retinoids also have a anti-inflammatory effect.

Is Aklief a prescription acne medication for adults only?

Aklief is given to treat acne in adults and children aged 9 and up. However, this medicine is only available at Oxford Online Pharmacy for adults over the age of 18 years old.  


Aklief (trifarotene) 75g cream for acne reviews

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How to use Aklief (trifarotene) 75g cream for acne

Always follow your doctor's instructions when using this medicine. If you have any doubts, get in touch with our healthcare team on 01295 262925.

Note: Aklief can be prescribed by our online doctors and should be applied exclusively to the face and/or upper body. You must avoid using it on other parts of the body.

It is important that you make sure the Aklief cream is out of reach of children.

How to apply Aklief Ceam?

  1. First of all you must prime the pump by pressing down several times until a small amount of cream is produced (up to 10 times maximum).
  2. To clean and dry skin, in the evening you should apply only a thin layer of cream to the affected areas.
  3. For the face (forehead, cheeks, nose, and chin), one pump should be enough.
  4. For the upper trunk (upper back, shoulders, and chest), two pump should be enough. If acne is present on the middle and lower back, an additional pump can be used.
  5. Using more than four pump actuations in a day is not recommended.

Avoid contact with eyes, eyelids, lips and inside the nose or mouth. If the cream accidentally comes into contact with these areas, wash them with lukewarm water straight away.

You must always wash your hands straight after applying the cream.

If you need to use a moisturiser during the Aklief treatment, it can be applied before or after Aklief, ensuring time for the skin to dry between applications so the cream can soak in.

Your doctor will decide how long you should use Aklief Cream for. After three months of treatment, your doctor may want to check the progress of your acne.

Who can use Aklief cream?

Aklief cream is suitable for acne sufferers over the age of 18.

Avoid using Aklief in the following situations:

  • If you are pregnant or planning on becoming pregnant
  • If you are allergic to trifarotene or to the other ingredients of this medicine.

Make sure you always read the warnings and precautions before using Aklief cream.

Possible side effects can occur, such as redness, peeling, dryness, and stinging/burning. If you experience these symptoms, get in touch and we will advise you on what to do next. Applying a moisturiser at the beginning of your treatment will help to prevent these reactions. If symptoms do occur, your doctor may advise you to use a moisturiser (if you haven't already), reduce the frequency of Aklief cream application, or temporarily discontinue its use. If these symptoms persist despite these measures, it may be advised to discontinue the use of Aklief cream altogether.

Additional precautions:

  • Do not use Aklief on cuts, scrapes, abraded, or eczematous skin.
  • Avoid contact with the eyes, eyelids, lips, or mucous membranes. If the product comes into contact with your eyes, rinse with lukewarm water.
  • Be cautious when applying it to sensitive areas like the neck or armpits.
  • Use caution when using Aklief cream concurrently with other skin products, including cosmetics.
  • If you experience any signs of sensitivity to the cream we advise that you discontinue the use of Aklief.
  • Do not apply Aklief to sunburnt skin you can prevent having to do this by avoiding excessive sun exposure during your treatment. 
  • Regarding other medications, inform your doctor about any other medicines you are currently using. 

How long does it take Aklief cream to work?

You should expect to start seeing results from using Aklief cream in as little as two weeks. If you don’t notice any improvement after the first 2 weeks, we advise consulting your doctor.

When is the best time of day to apply Aklief Cream?

Once a day, in the evening, apply Aklief Cream to the affected area. If you must be in the sun or are sensitive to it, use suncream with an SPF15 or more, as well as protective clothing and a hat to cover the treated areas.

How much Aklief Cream should I use?

1 pump is should be enough for your face. Use two pumps for your upper back, shoulders, and chest. You may use an additional pump for your middle to lower back if necessary. For more details, refer to the patient information leaflet.

What if I forget to apply Aklief Cream?

Do not duplicate the dose to compensate for the missed one. Simply repeat the process the next day with the same amount of product. To get the most out of your treatment, try to continue taking it as directed.

How long should I use Aklief Cream?

You may see an improvement in your facial acne as soon as two weeks. Patients in clinical trials were instructed to take Aklief Cream for 12 weeks, although, you should continue with your treatment as prescribed by your doctor Your doctor will advise you on how long you should use Aklief. After three months of treatment, your doctor may want to check on the progress of your acne. 


Side effects of Aklief (trifarotene) 75g cream for acne

Aklief cream side effects

As with all medications, this medicine may cause side effects, although not everyone experiences them. Aklief may lead to the following side effects:

Common side effects:

  • Skin irritation at the application site
  • Itching 
  • Sunburn

Uncommon side effects:

  • Skin pain
  • Swelling
  • Discoloration (loss of skin pigmentation)
  • Skin loss
  • Dry skin
  • Rash
  • Skin allergy
  • Redness

Rare side effects:

  • Hives
  • Skin-burning sensation
  • Skin fissures
  • Vesicles
  • Dry skin with scales and fissures
  • Red, scaly, and itchy skin 
  • Peeling of the eyelid skin
  • Swelling of the eyelid skin
  • Darkening of skin pigmentation
  • Chapped lips
  • Flushing

If you experience any of these Aklief Cream side effects or have concerns about them, get in touch and a member of our healthcare team will be happy to help.

Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Aklief (trifarotene) 75g cream for acne - Patient Information Leaflet

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References
  1. National Library of Medicine, Trifarotene: A Novel Therapeutic Option for Acne, Published online 2022 May 27. doi: 10.1155/2022/1504303
  2. National Library of Medicine, Trifarotene 0.005% Cream in the Treatment of Facial and Truncal Acne Vulgaris in Patients with Skin of Color: a Case Series, Published online 2022 Aug 22. doi: 10.1007/s13555-022-00788-w

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Authored on 14 December 2023

Robert Bradshaw

Robert Bradshaw - MRPharms BSc(Hons) Pharmacy

Superintendent Pharmacist

GPhC Number: 2036118

Reviewed on 14 December 2023

Kiran Jones

Kiran Jones - MPharm, MRPharmS

Pharmacist / Medical Content Writer

GPhC Number: 2071585

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