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Hezkue Sildenafil Oral Spray
Hezkue Sildenafil Oral Spray Product information
£57.95 (£57.95 per units)
| 30ml | |
|---|---|
| 1 units | £57.95 |
| 2 units | £107.99 |
| 3 units | £149.99 |
Hezkue Sildenafil Oral Spray 30ml
Hezkue Sildenafil oromucosal spray is a prescription treatment for erectile dysfunction (ED), helping men achieve firmer, longer-lasting erections. It contains sildenafil, the same active ingredient used in standard Sildenafil tablets, but is delivered as a spray inside the mouth rather than swallowed as a pill.
This medicine isn't intended to replace tablets for everyone, but offers an alternative if you dislike tablets, find them difficult to swallow, or want a more flexible way to adjust your dose.
Each 30 ml bottle contains enough medicine for between 5 and 20 doses depending on your prescribed strength, so one bottle can last several weeks.
Product Information for Hezkue Sildenafil Oral Spray
How does Sildenafil spray work?
Hezkue is a PDE5 inhibitor and works the same way as other sildenafil medicines. It helps relax blood vessels in the penis, allowing more blood to flow in during sexual stimulation (1). This increased blood flow is what helps you get and maintain an erection.
Unlike tablets, the spray delivers sildenafil through the lining of the mouth (the oromucosal route), where it is absorbed directly into the bloodstream rather than passing through the digestive system. It should start working 30 to 60 minutes after use, which is similar to sildenafil tablets.
As with all sildenafil treatments, the Hezkue spray doesn’t cause an automatic erection. Sexual stimulation is required for the medicine to work.
Benefits of the spray format
Hezkue Sildenafil spray may be suitable if you have difficulty getting or keeping an erection. The benefits are:
Fast absorption detected within 5 minutes vs. Viagra® tablets (2)*
Spray format for people who prefer not to swallow tablets or find tablets uncomfortable or difficult
Allows precise dose control using measured sprays (each spray delivers exactly 12.5 mg, so you can match standard sildenafil tablet strengths)
Discreet, portable and doesn't require water
*In a pharmacokinetic study of 52 fasted healthy male volunteers comparing 100 mg Hezkue spray with 100 mg Viagra tablets (Kaplan et al. 2024). The clinical significance of earlier absorption has not been evaluated.
It can be a helpful alternative if you are already familiar with sildenafil and want a different way to take it.
Who can and cannot use this medicine
The Hezkue Sildenafil spray is suitable for most adult men aged 18 or over with erectile dysfunction. However, you should not use this medicine if you (6):
Take nitrates or nicorandil for chest pain
Use poppers (combining these with sildenafil can cause a dangerous drop in blood pressure)
Have severe heart or blood pressure problems
Have had a recent heart attack or stroke
Have severe liver impairment
Have loss of vision in one eye
Have low blood pressure (below 90/50 mmHg)
Take riociguat, a medicine used for pulmonary arterial hypertension
You may need extra medical advice before using this treatment if you take alpha-blockers or medicines that affect how sildenafil is broken down in the body, have certain eye conditions or visual disorders, or have Peyronie’s disease or another condition that affects the shape of the penis.
Drinking alcohol can temporarily impair your ability to get an erection. You are advised not to drink excessive amounts of alcohol before taking this medicine (5).
This is why an online consultation is required. A doctor will be able to check your health, current medicines, and symptoms to make sure Hezkue is safe and appropriate for you.
Hezkue Sildenafil Oral Spray reviews
How to use Hezkue Sildenafil Oral Spray
It's recommended to use the spray approximately 60 minutes before you plan to have sex (3). You can take it with or without food, however taking it after a heavy meal may delay how quickly it starts to work. For this reason, some people prefer to use it on an empty stomach.
Before using the spray, check your dose so you know how many sprays you need. Most men are advised to start with four sprays (50 mg) (3). Depending on how the medicine works for you, this may be reduced to two sprays (25 mg), especially with certain medical conditions, or increased to a maximum of eight sprays (100 mg).
Number of Pumps | Sildenafil Administered | Total Number of doses in a Bottle |
|---|---|---|
2 | 25mg | 20 |
4 | 50mg | 10 |
8 | 100mg | 5 |
You also need to prime the pump before each use to make sure it delivers the correct dose. To do this:
Shake the bottle to mix the suspension
Remove the lid and replace it with the dosage cap
Press the pump three times to activate it
If any medicine is released, discard it
Your spray is now ready to use. Open your mouth and spray the number of sprays prescribed by your doctor against the inside of your cheek. Swallow straight away. It’s important not to take more than your prescribed dose and not to take more than 100mg in 24 hours. Always read the full instruction and usage leaflet before using.
If you accidentally take too much, seek medical advice straight away.
Once opened, the bottle should be used within 10 months (5). It does not require any special storage conditions, but should be kept out of the reach of children.
Side effects of Hezkue Sildenafil Oral Spray
Sildenafil spray can cause side effects, but not everyone gets them. These side effects are the same as other sildenafil medicines. Common side effects include (3):
Headache — very common, may affect more than 1 in every 10 people
Flushing — may affect up to 1 in every 10 people
Nasal congestion — may affect up to 1 in every 10 people
Indigestion or nausea — may affect up to 1 in every 10 people
Dizziness — may affect up to 1 in every 10 people
Visual disturbances, including blurred vision or changes to colour vision (such as a blue tint) — may affect up to 1 in every 10 people
Less common side effects (affecting up to 1 in 100 people) may include skin rash, watery eyes, palpitations, a fast heartbeat, muscle aches, drowsiness, or a feeling of numbness or tingling (3).
Seek urgent medical attention if you experience:
Chest pain during or after sexual activity
Sudden loss of vision in one or both eyes
Sudden decrease or loss of hearing
An erection lasting longer than 4 hours (priapism)
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The spray has been shown to begin absorbing into the bloodstream within minutes, but a noticeable effect on erections is usually expected within 30 to 60 minutes. This can vary between individuals and may be affected by whether you have recently eaten a heavy meal.
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The effects of sildenafil typically last 4 to 5 hours. This doesn't mean you will have an erection for that long — it means the medicine is active in your system during that window, and you may find it easier to achieve an erection with sexual stimulation during this time.
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It contains the same active ingredient and is not more effective (it’s just a different delivery format). Different delivery methods work differently for each individual.
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Sexual stimulation is required for the sildenafil spray to work. The medicine supports the body's natural response to arousal — it does not create one on its own.
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You should not use this spray at the same time as other ED medicines, including other PDE5 inhibitors such as tadalafil (Cialis) or vardenafil (Levitra), or any other treatments for erectile dysfunction (3).
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Each 30 ml bottle provides up to 20 doses at 25 mg, 10 doses at 50 mg, or 5 doses at 100 mg (3).
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The spray has a mint flavour.
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Sildenafil has been studied in men with these conditions and has shown to be effective (7). However, your doctor will need to assess your overall health and any other medicines you take before prescribing it.
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No. Hezkue does not require any special storage conditions. Once opened, it should be used within 10 months (5).
Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)
1. NHS. About Sildenafil (Viagra) 2022.
2. Kaplan SA, Moore J, Niecestro R. Pharmacokinetic Parameters of a Novel Sildenafil Oral Liquid Suspension Administered to Healthy Adult Men Under Fasted Conditions. Int J Sci Res. 2024;13(6):759-64.
3. Hezkue 12.5 mg/actuation, white to off-white oromucosal suspension with a mint aroma flavour - Summary of Product Characteristics (SmPC) - (emc) | 101466. 2025.
4. Hezkue Pharmacy Guide. Aspargo Labs. October 2025.
5. Hezkue 12.5 mg/actuation, oromucosal spray, suspension — Patient Information Leaflet. December 2024.
6. NHS. Who can and cannot take sildenafil. 2022.
7. Hezkue SmPC, Section 5.1 — Clinical trial data across patient populations including diabetes mellitus and hypertension.
- Sildenafil tablets vs Hezkue sildenafil spray: which is right for you?
- ED Sprays: Do they work and are they safe?
- Do I need to go to my GP for Erectile Dysfunction? Explore your options
- How blood affects erections: the science behind erectile dysfunction
- Why do ED medicines work for some people but not others?
- What is PDE5, and how do PDE5 inhibitors work?
- What we ask (and why) before we prescribe
- Can erectile dysfunction go away on its own?
- Comparing ED treatments, what do men try first?
- Can you have ED and still be healthy?
Authored on March 28, 2026
Reviewed on March 29, 2026
Robert Bradshaw (Pharmacist) - MRPharms BSc(Hons) Pharmacy
Superintendent Pharmacist
GPhC Number: 2036118