Novofem (Estradiol 1mg / Norethisterone 1mg) 84 Tablets

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Novofem (Estradiol/Norethisterone) Tablets 84 is a sequential combined Hormone Replacement Therapy (HRT). It is taken every day without interruption. It contains two female hormones an Oestrogen-Estradiol and a Progestagen-Norethisterone. Novofem is used for the relief of symptoms occurring after menopause and is the secondary treatment choice for postmenopausal women who are at high risk of fractures but are unable to take other medications approved for osteoporosis prevention.

Novofem is a sequential combination hormone replacement therapy (HRT) administered to postmenopausal women who have had at least six months since their last natural menstruation and should be taken without interruption every day. It contains an oestrogen (estradiol) and a progestogen (norethisterone acetate), two hormones. As a natural oestrogen, the estradiol in Novofem is the same as the estradiol produced in female ovaries. Synthetic progestagen norethisterone acetate functions similarly to progesterone, another crucial female sex hormone.

There are two types of tablets in each pack. The white tablets contain estradiol and norethisterone, while the red tablets only contain estradiol.  These are variations of oestrogen and progesterone, the two primary female sex hormones.

In the years leading up to menopause, women's ovaries gradually generate less and less oestrogen, which causes their blood levels of oestrogen to drop. Symptoms such as irregular periods, hot flushes, night sweats, mood swings, and itchy or dry vagina could present due to low oestrogen levels.

Oestrogen can be used as a supplement to replenish the body's declining levels and help ease these uncomfortable menopause symptoms. HRT is the term used to describe this (HRT). 

For women who have not had a hysterectomy, HRT must include a progestogen. This is because of the fact that in females with an intact womb, oestrogen stimulates the growth of the endometrium, which, if unchecked, can result in endometrial cancer. Progestogens are administered to counteract oestrogen's impact on the uterine lining and lower the chance of cancer, although they do not completely eradicate it.

Novofem is a sequential variation of combined HRT. This means that progestogen is added for a portion of each month whereas oestrogen is consumed continuously. Only estradiol is found in the red Novofem pills taken during the first 16 days of each cycle. Estradiol and norethisterone are both included in the white tablets that are taken during the following 12 days of each cycle. Because this type of HRT typically causes a monthly bleed at the end of using the white tablets, it is better suited for women who are still experiencing irregular periods.

Osteoporosis is a disorder where the bones grow thinner and more brittle due to the diminishing oestrogen levels that occur after menopause. In order to assist in preventing bone loss and fractures that may occur in women in the years following menopause, oestrogen can also be supplemented.