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Sons Ketoconazole 2% Anti-Dandruff Shampoo Rear view of Sons Ketoconazole 2% Anti-Dandruff Shampoo Pill view of Sons Ketoconazole 2% Anti-Dandruff Shampoo

Sons Ketoconazole 2% Anti-Dandruff Shampoo

Sons Ketoconazole 2% Anti-Dandruff Shampoo Product information

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Dandruff is very common in the UK, affecting a significant number of adults, although exact figures aren’t available. Scalp fungal infections are much less often in adults but both cause flaking, itching and irritation that can impact your day-to-day life.

Ketoconazole shampoo is an effective treatment for dandruff and fungal scalp infections and works by disrupting or destroying the yeast/fungus linked to dandruff and scalp infections, particularly Malassezia– a type of fungus that naturally lives on the skin which can overgrow and trigger an inflammatory response. It also reduces inflammation that causes itching and flaking (1).

Product Information for Sons Ketoconazole 2% Anti-Dandruff Shampoo

What is Ketoconazole anti-dandruff shampoo?

Sons Ketoconazole 2% shampoo is an anti-dandruff shampoo containing the active ingredient Ketoconazole– a pharmacological anti-fungal treatment for dandruff and fungal scalp infections.

How does Ketoconazole anti-dandruff shampoo work?

Ketoconazole shampoo works by targeting the yeast/fungus responsible for dandruff (Malasezzia) and fungal scalp infections.

Malasezzia is a yeast-like fungi that naturally lives on human skin, particularly oily areas such as your scalp. In some people, changes in Malasezzia levels or skin sensitivity can cause dandruff (pityriasis capitis) or an inflammatory skin condition called seborrheic dermatitis and other scalp problems (1).

Ketoconazole disrupts the fungus, preventing cell production so that the fungus is unable to grow properly. This mechanism keeps flaking, itchiness and irritation under control (2).

How quickly will Ketoconazole work to stop my dandruff?

Most people start to notice an improvement in their symptoms within 2 weeks of starting treatment, with optimal results usually being achieved between 2 and 4 weeks when Ketoconazole is used consistently (2).

A clinical trial of 2% ketoconazole shampoo, the ketoconazole formulation significantly reduced both flakiness and Malassezia density from baseline after 2 and 4 weeks of treatment (2).

To get the best results:

  • Use twice a week (with at least 3 days between uses)

  • Leave it on the scalp for the recommended contact time before rinsing (see directions for use)

  • Stick with it for the full course, even if symptoms start to ease early

  • If you see no improvement after 4–6 weeks, speak to a pharmacist or your GP

Sons Ketoconazole 2% Anti-Dandruff Shampoo reviews

How to use Sons Ketoconazole 2% Anti-Dandruff Shampoo

To use Ketoconazole shampoo, wet your scalp and hair thoroughly using clean, warm water. Apply enough of the shampoo to your head so that when you lather it, it completely covers your scalp. Gently massage it in and leave it for between 3 and 5 minutes. This gives time for the active ingredient to be absorbed into your skin. Then rinse well with water until there is no shampoo left. Make sure to wash your hands after, to avoid getting the shampoo into your eyes and mouth (4).

How often should I use Ketoconazole shampoo?

For dandruff or seborrhoeic dermatitis, the usual recommendation is to use Ketoconazole shampoo twice each week for 2 to 4 weeks. After this time, if your symptoms have improved you may only need to use the shampoo once every 1 to 2 weeks to stop your symptoms returning.

Using Ketoconazole shampoo alongside steroid treatment

If your scalp is extremely red, inflamed or itchy, you may be recommended to use Ketoconazole shampoo alongside a topical steroid treatment. The steroid works to reduce inflammation and suppresses your immune system response. It is usually applied in a thin layer directly to the affected skin on your scalp (5).

Please note: If you are taking long-term topical steroids such as betamethasone or hydrocortisone, you should discuss how to use Sons Ketoconazole alongside your steroid treatment with your prescriber. Do not stop taking your steroids suddenly and without speaking to a medical professional first.

How should I store Ketoconazole shampoo?

  • Do not store Ketoconazole shampoo above 25°C.

  • Store in original packaging, with the lid tightly closed, out of the sight and reach of children.

  • Do not store in direct sunlight.

  • Do not use Ketoconazole shampoo after the expiry date which should be displayed on the label or carton. The expiry date is the last date of that month.

  • Do not dispose with your household waste. Instead, speak to your pharmacist about the best way to dispose of Ketoconazole shampoo (4).

Side effects of Sons Ketoconazole 2% Anti-Dandruff Shampoo

As with all medications, there are some side effects associated with Ketoconazole shampoo that you should be aware of, although not everyone gets them.

Uncommon side effects include:

  • Application site reactions, such as itching, irritation, blistering, redness, dryness, tenderness or burning sensation.

  • Inflamed hair follicles.

  • Hair loss or changes in hair texture.

  • Increased tear production.

  • Skin rash/dry skin.

Rare side effects include:

  • Change in taste.

  • Eye irritation.

  • Acne and/or dermatitis.

  • Flaking skin.

If you experience any symptoms of an allergic reaction, such as swelling of your throat, tongue, mouth or face, difficulty breathing or an extensive rash, discontinue use immediately and seek medical help (4).

You should not use Ketoconazole shampoo if you are allergic to any of the ingredients, including benzyl alcohol and sodium laurilsulfate (4). Patients with a known history of "multiple contact dermatitis" or sensitivity to detergents should perform a small patch test or consult a pharmacist specifically about the Sodium Laurilsulfate (SLS) content, as it is a known irritant.

Frequently Asked Questions
Patient Information Leaflet

Important - Before taking any medication, it is always important to read the Patient Information Leaflet (PIL)

Sons Ketoconazole 2% Anti-Dandruff Shampoo - Patient Information Leaflet

References
  1. Kim GK. Seborrheic Dermatitis and Malassezia species: How Are They Related? The Journal of Clinical and Aesthetic Dermatology [Internet]. 2009 Nov [cited 2026 Aug 5];2(11):14.

  2. Effect of ketoconazole 1% and 2% shampoos on severe dandruff and seborrhoeic dermatitis: clinical, squamometric and mycological assessments [Internet]. Dermatology; 2001.

  3. Tao R, Wang R, Wan Z, Song Y, Wu Y, Li R. Ketoconazole 2% cream alters the skin fungal microbiome in seborrhoeic dermatitis: a cohort study. Clinical and experimental dermatology [Internet]. 2022 June [cited 2026 Aug 5];47(6):1088–96.

  4. Pinewood Healthcare. Ketoconazole 2% w/w Shampoo: Patient Information Leaflet [Internet]. Dublin: Pinewood Healthcare; 2025 [cited 2026 Aug 05].

  5. Mir-Bonafé JF, Piquero-Casals J, Prudkin L, Delgado J, Martínez JS, Briones VGP. Use of Topical Corticosteroids in the Treatment of Noninfectious Inflammatory Dermatoses of the Scalp: A Survey of Practicing Dermatologists and Dermatology Residents Using Delphi Methodology. Clinical, Cosmetic and Investigational Dermatology [Internet]. 2024 Mar 18 [cited 2026 Aug 5];17:671–81.

  6. Tynes BE, Johnson C D, Vaish MH, Abbott B, Jelena Vučenović, Giustino Varrassi, et al. Ketoconazole Shampoo for Seborrheic Dermatitis of the Scalp: A Narrative Review. Cureus [Internet]. 2024 Aug 22 [cited 2026 Aug 5];.

  7. NHS Choices. Who can and cannot use ketoconazole - Brand names: Daktarin Gold, Daktarin Intensiv, Dandrazol, Nizoral [Internet]. 2024 [cited 2026 Aug 5].

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Authored on August 25, 2026

Robert Bradshaw (Pharmacist)

Robert Bradshaw (Pharmacist) — MRPharms BSc(Hons) Pharmacy

Superintendent Pharmacist

GPhC Number: 2036118

GMC Number: 20399999

Reviewed on August 26, 2026